The Prospective Drug Discovery Autism

After the success at the level of the study, researchers hope the drug could be used to bid symptoms of autism in humans.

United State National Institutes of Health examined the use of drugs GRN-529 to reduce the common symptoms that are often shown by people living with autism. The drug may help brain cells communicate two with each other.

Although had been circulating the notion that autism is a disorder that can not be addressed with medication, researchers believe that the use of these drugs can reduce the symptoms of autism. How, by seeking to brain cells communicate at synapses - the gaps between the cells of the human brain.

The test performed on behaving rats with autism - is in contrast to mice that did develop autism. "Autistic mice" lacking in terms of socialization and communication with other mice. They also spend a lot of time to perform activities related to repeated himself.

Once injected, the rats showed a better behavior. Such as reducing the repetitive activity and demonstrate the improvement in the social level. The researchers believe these findings enhance the chances of the drug can be used in the treatment of autism.

"Given the high cost, both in money and emotional, to families, schools and health care system, we hope the series can meet the needs of drugs that address the underlying symptoms," said Dr. Jacqueline Crawley, one of the researchers from the National Institute of Mental Health.

Uta Frith, professor of cognitive development from University College London said: "The processes at synapses has long been suspected as the origin of autism."

The study, published in the journal Science Translational Medicine is even showing positive symptoms in mice, not simply be applied to humans. It took a long time and a series of further research to test its feasibility in humans. In fact rarely even fail a drug applied to humans even if successful in animals.

Autistic behaviors known to affect 1 percent of the children. The scale varies from mild to severe. Symptoms range from social constraints, language barriers, and like to repeat as mengetukan hand movements. So far, people with autism treated through special education such as speech and behavioral therapy.

New Drug for Pancreatic Cancer

Scientists from the British managed to find a cure for pancreatic cancer. According to scientists from Cancer Research UK, aggressive pancreatic cancer may be cured by this drug.

Tumors or cancer of the pancreas is extremely dangerous. Only one in five people who can survive for a year after being diagnosed. This is because the gene is turned off by people with cancer cells.

Now, researchers are testing drugs that have the potential to alter gene and stop the spread of cancer cells. This treatment has been practiced to mice indicate that USP9x gene, which controls the cell to divide, turned off by the cancer cells.

Gene is not mutated, but proteins and other chemicals and make the gene stops dead. "We suspect that the fault is not in the genetic code, but a chemical that turns the gene off or on. After some more tests, we will confirm, "said researchers from the Cancer Research UK, David Tuveson.

Researchers from the Wellcome Trust Sanger Institute, David Adams, said that this study strengthens our understanding of biological cells. "We have to look into cell biological systems to identify all the genes that play a role in cancer," he explained.

Each year, approximately 7,800 people in the UK are diagnosed with pancreatic cancer. Pancreatic cancer is dangerous, to belong to the five most deadly cancers.

U.S. Support Prevent HIV pills for Healthy People

U.S. health panel for the first time support the use of HIV prevention drug to healthy people.

Panel recommends U.S. regulators to approve a daily pill, Truvada, to be used by healthy people who are considered at high risk of the virus that causes AIDS. Previously a number of health workers and community groups are active in refusing HIV drugs. The rejection was based on the consideration that the user will get a false sense of security and fears of the emergence of a new type of HIV drug resistance.

On the other hand, those who support the Truvada reasoned that the use of the drug solely for HIV prevention efforts. That effort was not to be used as a single effort of prevention, because other efforts continue to run as a safe sex campaign, use of protective equipment, and routine testing.

Truvada long as it's used for people with HIV and drug use in conjunction with anti-retroviral drugs. Results of the study in 2010 showed that Truvada, a drug made ​​by Gilead Sciences, based in California, can reduce HIV risk in healthy homosexual men and also for HIV among heterosexual HIV-negative but have positive partners, between 44 percent to 73 percent.

Food and drug watchdog U.S. FDA panel will consider the proposal and is expected to make a final decision on 15 June.

One-third of Malaria Drugs in the World is Fake

Third of malaria drugs are used around the world to stem the disease proved to be false.

The findings are revealed in The Lancet Infectious Diseases study that examines approximately 1,500 samples from seven malaria drugs from seven countries in Southeast Asia.

They claimed that malaria drugs are very low quality and fake that cause drug resistance and treatment failure.

In addition to Southeast Asia, experts from research institutes also found similar data in 21 countries of sub-Saharan Africa after testing more than 2,500 drug samples.

A number of observers to assess the health problems of these findings is a'' warning''.

The researchers from the Fogarty International Center at the National Institute of Health (NIH) who participated in this study believe that this problem may be much larger than the data revealed.

"Most cases probably go unreported, reported to the wrong institution, or remain anonymous by drug companies,'' said the researcher.

Minimal supervision

After all the research related to drug quality has never been done extensively in China or India - a country with one third of world population and'' likely'' source of many counterfeit drugs, including anti-malaria drugs.

Nayyar Gaurvika lead researcher emphasized that the 3.3 billion people at risk of malaria, which has been classified as endemic in 106 countries.

"Between 655 000 and 1.2 million people die each year from Plasmodium falciparum infection,'' he said.

'' Most of this morbidity and mortality can be avoided if the drug available to patients nutritious, high quality, and used properly.''

This study also found that many facilities are not adequate to monitor the quality of anti-malaria drugs and low knowledge of consumers and health professionals over medication therapy.

And also found a lack of regulation that oversees the drug manufacturer and the lack of penalties for counterfeiters.

However, the malaria mortality rate has dropped more than 25% globally since 2000, and by 33% in the African region.

But the UN health organization, WHO said that maintaining the current rate of progress will not be sufficient to meet the target of malaria control globally.

This requires investment in the renewal of diagnostic testing, treatment, and surveillance for malaria.

H1N1 Flu Vaccine profitable Pregnant

Nobody wants to get the flu. However, for pregnant women, get the influenza vaccination was found to provide a distinct advantage.

A team of researchers from Canada found that the H1N1 virus vaccine did not cause any side effects for the mother. Instead, the vaccine is given when the mother teserang flu can significantly reduce mortality at birth and that cause premature birth-weight babies born too small.

"It's surprising, but also attractive. This discovery is one example of the relationship between flu vaccination and infant mortality at birth. It's something rare going on," said Deshayne Fell, researchers from McGill University, a research associate with infant mortality data.

The researchers found that pregnant women who received the H1N1 vaccine has health benefits multiply. Avoid as much as 34 percent of newborn deaths, 28 percent to avoid premature delivery, and 19 children born with a good weight. In this study, the researchers used a database of data delivery in Ontario. There are at least 55 570 births in Ontario during the H1N1 pandemic are studied by researchers.

"This discovery is very useful. Pregnant women will usually be very careful with what you put into their bodies. However, it H1N1 will help them to treat the flu and also bring other benefits for the baby," said Mark Walker, a member team of researchers from the University of Ottawa.

Written in a paper titled "H1N1 Influenza Vaccination During Pregnancy and Fetal and Neonatal Outcomes", the study also published in the American Journal of Public Health.